Recombinant Mouse Epha1, GST-tagged, Active

• Cat.No.: Epha1-299M
• Product Overview: Recombinant mouseEpha1 (569-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MW=71 kDa.

Specification

• Species: Mouse
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 569-end a.a.
• Description: Epha1 is a member of the Eph family of receptor tyrosine kinases that have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the Eph subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. EPHA1 seems to be a marker of the differentiated normal epidermis and its downregulation in nonmelanoma skin cancer may contribute to carcinogenesis of these very frequent human tumors. EPHA1 represents a new potential prognostic marker and therapeutic target in nonmelanoma skin cancer.
• Sequence: 569-end.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70^oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: Epha1 Eph receptor A1 [ Mus musculus ]
• Synonyms: Epha1; Eph receptor A1; Eph; Esk; AL033318; 5730453L17Rik; ephrin receptor EphA1; EC 2.7.10.1
• Gene ID: 13835
• mRNA Refseq: NM_023580
• Protein Refseq: NP_076069
• UniProt ID: Q60750
• Chromosome Location: 6 B2.1
• Pathway: Axon guidance
• Function: ATP binding; ephrin receptor activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; receptor activity; transmembrane receptor protein tyrosine kinase activity