Recombinant Mouse Eph Receptor B2

• Cat.No.: Ephb2-1727M

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Non
• Description: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
• Molecular Weight: The predicted molecular weight of Recombinant Mouse EphB2 is Mr 85.3 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 100-110 kDa.
• State Of Matter: Lyophilized.
• Purity: >90% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Ephb2 Eph receptor B2 [ Mus musculus ]
• Synonyms: Ephb2; Eph receptor B2; Drt; Erk; Nuk; Cek5; Hek5; Qek5; Sek3; ETECK; Prkm5; Tyro5; OTTMUSP00000010323; EC 2.7.10.1
• Gene ID: 13844
• mRNA Refseq: NM_010142
• Protein Refseq: NP_034272
• UniProt ID: P54763
• Chromosome Location: 4 D-E; 4 65.7 cM
• Pathway: Axon guidance
• Function: ATP binding; axon guidance receptor activity; ephrin receptor activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein tyrosine kinase activity; receptor activity; receptor binding; transferase activity; transmembrane receptor protein tyrosine kinase activity; transmembrane-ephrin receptor activity