Recombinant Mouse Eph Receptor A3

• Cat.No.: Epha3-1723M

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Non
• Description: EPH receptor A3 (ephrin type-A receptor 3) is a protein that in humans is encoded by the EPHA3 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.
• Molecular Weight: The predicted molecular weight of Recombinant Mouse EphA3 is Mr 86 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 110 kDa.
• State Of Matter: Lyophilized.
• Purity: >90% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Epha3 Eph receptor A3 [ Mus musculus ]
• Synonyms: Epha3; Eph receptor A3; Hek; Cek4; ETK1; End3; Hek4; Mek4; Tyro4; AW492086; ephrin receptor EphA3; EC 2.7.10.1
• Gene ID: 13837
• mRNA Refseq: NM_010140
• Protein Refseq: NP_034270
• UniProt ID: P29319
• Chromosome Location: 16 C1.3
• Pathway: Axon guidance
• Function: ATP binding; ephrin receptor activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein tyrosine kinase activity; receptor activity; transferase activity; transmembrane receptor protein tyrosine kinase activity