Recombinant Mouse Eif2s2 Protein, Myc/DDK-tagged

• Cat.No.: Eif2s2-2776M
• Product Overview: Purified recombinant protein of mouse full-length eukaryotic translation initiation factor 2, subunit 2 (beta) (Eif2s2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
• Molecular Mass: 38.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Eif2s2 eukaryotic translation initiation factor 2, subunit 2 (beta) [ Mus musculus (house mouse) ]
• Official Symbol: Eif2s2
• Synonyms: EIF2S2; eukaryotic translation initiation factor 2, subunit 2 (beta); eukaryotic translation initiation factor 2 subunit 2; eIF-2-beta; eukaryotic translation initiation factor 2 subunit beta; eukaryotic translation initiation factor 2, subunit 2 (beta, 38kDa); EIF2; 38kDa; EIF2B; AA408636; AA571381; AA986487; AW822225; D2Ertd303e; 2810026E11Rik; MGC130606
• Gene ID: 67204
• mRNA Refseq: NM_026030
• Protein Refseq: NP_080306
• UniProt ID: Q99L45