Recombinant Mouse Ebp Protein, Myc/DDK-tagged

• Cat.No.: Ebp-2713M
• Product Overview: Purified recombinant protein of mouse full-length phenylalkylamine Ca2+ antagonist (emopamil) binding protein (Ebp), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a transmembrane protein that localizes to the endoplasmic reticulum. This protein catalyses the conversion of delta8 to delta7 sterols, an important step in sterol biosynthesis. Mutations in this gene are responsible for the mouse tattered mutant phenotype. Tattered males are embryonic lethal, while heterozygous females have developmental defects. Deficiency of the related gene in human causes X-linked dominant chondrodysplasia punctata.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 26.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ebp phenylalkylamine Ca2+ antagonist (emopamil) binding protein [ Mus musculus (house mouse) ]
• Official Symbol: Ebp
• Synonyms: EBP; phenylalkylamine Ca2+ antagonist (emopamil) binding protein; 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase; tattered; D8-D7 sterol isomerase; emopamil-binding protein; cholestenol Delta-isomerase; delta(8)-Delta(7) sterol isomerase; Td; mSI; Pabp; AI255399
• Gene ID: 13595
• mRNA Refseq: NM_007898
• Protein Refseq: NP_031924
• UniProt ID: P70245