Recombinant Mouse Dstyk Protein, Myc/DDK-tagged

• Cat.No.: Dstyk-2666M
• Product Overview: Purified recombinant protein of mouse full-length dual serine/threonine and tyrosine protein kinase (Dstyk), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.
• Molecular Mass: 105.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dstyk dual serine/threonine and tyrosine protein kinase [ Mus musculus (house mouse) ]
• Official Symbol: Dstyk
• Synonyms: DSTYK; dual serine/threonine and tyrosine protein kinase; dusty PK; dusty protein kinase; receptor interacting protein kinase 5; receptor-interacting serine/threonine-protein kinase 5; Ripk5; C820013G01; A930019K20Rik; C430014H23Rik
• Gene ID: 213452
• mRNA Refseq: NM_172516
• Protein Refseq: NP_766104
• UniProt ID: Q6XUX1