Recombinant Mouse Dok2 Protein, Myc/DDK-tagged

• Cat.No.: Dok2-2630M
• Product Overview: Purified recombinant protein of mouse full-length docking protein 2 (Dok2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.
• Molecular Mass: 45.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dok2 docking protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Dok2
• Synonyms: DOK2; docking protein 2; dok-R; p56 dok-2; p56(dok-2); dok-related protein; downstream of tyrosine kinase 2; IL-Four Receptor Interacting Protein; IL-four receptor-interacting protein; DokR; Frip
• Gene ID: 13449
• mRNA Refseq: NM_010071
• Protein Refseq: NP_034201
• UniProt ID: O70469