Recombinant Mouse Diablo Protein, Myc/DDK-tagged

• Cat.No.: Diablo-2563M
• Product Overview: Purified recombinant protein of mouse full-length diablo, IAP-binding mitochondrial protein (Diablo), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 26.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Diablo diablo, IAP-binding mitochondrial protein [ Mus musculus (house mouse) ]
• Official Symbol: Diablo
• Synonyms: DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; Smac; AU040403; 0610041G12Rik; 1700006L01Rik
• Gene ID: 66593
• mRNA Refseq: NM_023232
• Protein Refseq: NP_075721
• UniProt ID: Q9JIQ3