Recombinant Mouse Dhcr24 Protein, Myc/DDK-tagged

• Cat.No.: Dhcr24-2542M
• Product Overview: Purified recombinant protein of mouse full-length 24-dehydrocholesterol reductase (Dhcr24), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 60.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dhcr24 24-dehydrocholesterol reductase [ Mus musculus (house mouse) ]
• Official Symbol: Dhcr24
• Synonyms: Dhcr24; 24-dehydrocholesterol reductase; sela; mKIAA0018; 2310076D10Rik; 5830417J06Rik; delta(24)-sterol reductase; 3-beta-hydroxysterol delta-24-reductase; seladin-1; EC 1.3.1.72
• Gene ID: 74754
• mRNA Refseq: NM_053272
• Protein Refseq: NP_444502
• UniProt ID: Q8VCH6