Recombinant Mouse Dguok Protein, Myc/DDK-tagged

• Cat.No.: Dguok-2541M
• Product Overview: Purified recombinant protein of mouse full-length deoxyguanosine kinase (Dguok), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 32.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dguok deoxyguanosine kinase [ Mus musculus (house mouse) ]
• Official Symbol: Dguok
• Synonyms: DGUOK; deoxyguanosine kinase; deoxyguanosine kinase, mitochondrial; dGK; dGK1; dGK2; dGK3
• Gene ID: 27369
• mRNA Refseq: NM_013764
• Protein Refseq: NP_038792
• UniProt ID: Q9QX60