Recombinant Mouse Daam1 Protein, Myc/DDK-tagged

• Cat.No.: Daam1-2444M
• Product Overview: Purified recombinant protein of mouse full-length dishevelled associated activator of morphogenesis 1 (Daam1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells. Together with DAAM2, required for myocardial maturation and sarcomere assembly.
• Molecular Mass: 123.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Daam1 dishevelled associated activator of morphogenesis 1 [ Mus musculus (house mouse) ]
• Official Symbol: Daam1
• Synonyms: Daam1; dishevelled associated activator of morphogenesis 1; disheveled-associated activator of morphogenesis 1
• Gene ID: 208846
• mRNA Refseq: NM_026102
• Protein Refseq: NP_080378
• UniProt ID: Q8BPM0