Recombinant Mouse Cyp11b1 Protein, His&SUMO-tagged

• Cat.No.: Cyp11b1-889M
• Product Overview: Recombinant Mouse Cyp11b1 Protein (Met1-Asn501) with His&SUMO tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His&SUMO
• Protein Length: Met1-Asn501
• Description: Enables corticosterone 18-monooxygenase activity. Acts upstream of or within glucocorticoid biosynthetic process. Located in mitochondrion. Is expressed in adrenal gland; gland; lung; and testis. Used to study congenital adrenal hyperplasia. Human ortholog(s) of this gene implicated in several diseases, including congenital adrenal hyperplasia; corticosterone methyloxidase deficiency 1; diabetes mellitus (multiple); hypertension (multiple); and primary hyperaldosteronism (multiple). Orthologous to human CYP11B1 (cytochrome P450 family 11 subfamily B member 1) and CYP11B2 (cytochrome P450 family 11 subfamily B member 2).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 71.4 kDa; Accurate Molecular Mass: 71 kDa
• Purity: > 80%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Cyp11b1 steroid-11-beta-hydroxylase [ Mus musculus (house mouse) ]
• Official Symbol: Cyp11b1
• Synonyms: CYP11B1; steroid-11-beta-hydroxylase; Cyp11b; Cyp11b-1
• Gene ID: 110115
• mRNA Refseq: NM_001033229
• Protein Refseq: NP_001028401
• UniProt ID: Q3TG86