Recombinant Mouse Cyfip2 Protein, Myc/DDK-tagged

• Cat.No.: Cyfip2-2407M
• Product Overview: Purified recombinant protein of mouse full-length cytoplasmic FMR1 interacting protein 2 (Cyfip2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Part of the WAVE1 complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.
• Molecular Mass: 146.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cyfip2 cytoplasmic FMR1 interacting protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Cyfip2
• Synonyms: CYFIP2; cytoplasmic FMR1 interacting protein 2; cytoplasmic FMR1-interacting protein 2; p53-inducible protein 121; Pir121; AA930218; AU022376; mKIAA1168; 1500004I01Rik; 6430511D02Rik
• Gene ID: 76884
• mRNA Refseq: NM_133769
• Protein Refseq: NP_598530
• UniProt ID: Q5SQX6