Recombinant Mouse Cnot7, His-tagged

• Cat.No.: Cnot7-3640R
• Product Overview: CNOT7, 1-248aa, Mouse, His tag, E.coli

Specification

• Description: CNOT7, also known as CCR4-Not transcription complex, subunit 7, is a ubiquitous transcription factor. It is a component of the CCR4 complex which functions as a general transcription regulation complex. CNOT7 also binds to an anti-proliferative protein, B-cell translocation protein 1 (BTG1), which negatively regulates cell proliferation. Recombinant mouse CNOT7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
• Source: E.coli
• Species: Mouse
• Tag: His
• Form: Liquid
• Molecular Mass: 31.1 kDa (271aa), confirmed by MALDI-TOF
• Purity: >80% by SDS - PAGE.
• Storage: Can be stored at 4oC short term (1-2 weeks). For long term storage, aliquot and store at -20oC or - 70oC. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)
• Storage Buffer: 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
• Protein length: 1-248 a.a.

Gene Information

• Gene Name: Cnot7 CCR4-NOT transcription complex, subunit 7 [ Mus musculus ]
• Official Symbol: Cnot7
• Synonyms: CNOT7; CCR4-NOT transcription complex, subunit 7; CCR4-NOT transcription complex subunit 7; CAF-1; POP2 homolog; CCR4-associated factor 1; catabolite repressor protein (CCR4)-associative factor 1; Caf1; Pop2; AU022737
• Gene ID: 18983
• mRNA Refseq: NM_011135
• Protein Refseq: NP_035265
• Pathway: Deadenylation of mRNA, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Gene Expression, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem
• Function: nucleic acid binding; protein binding