Recombinant Mouse Cnep1r1 Protein, Myc/DDK-tagged

• Cat.No.: Cnep1r1-2216M
• Product Overview: Purified recombinant protein of mouse full-length CTD nuclear envelope phosphatase 1 regulatory subunit 1 (Cnep1r1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 14.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cnep1r1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 [ Mus musculus (house mouse) ]
• Official Symbol: Cnep1r1
• Synonyms: Cnep1r1; CTD nuclear envelope phosphatase 1 regulatory subunit 1; NEP1-R1; Tmem188; 5033428A16Rik; nuclear envelope phosphatase-regulatory subunit 1; transmembrane protein 188
• Gene ID: 382030
• mRNA Refseq: NM_029074
• Protein Refseq: NP_083350
• UniProt ID: Q3UJ81