Recombinant Mouse Cdc42 Protein, MYC/DDK-tagged

• Cat.No.: Cdc42-856M
• Product Overview: Purified recombinant protein of full-length mouse cell division cycle 42 (Cdc42), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 21.7 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cdc42 cell division cycle 42 [ Mus musculus (house mouse) ]
• Official Symbol: Cdc42
• Synonyms: Cdc42; cell division cycle 42; AI747189; AU018915; cell division control protein 42 homolog; G25K GTP-binding protein
  cell division cycle 42 homolog; EC 3.6.5.2
• Gene ID: 12540
• mRNA Refseq: NM_009861
• Protein Refseq: NP_033991
• UniProt ID: P60766