Recombinant Mouse Ccny Protein, Myc/DDK-tagged

• Cat.No.: Ccny-2050M
• Product Overview: Purified recombinant protein of mouse full-length cyclin Y (cDNA clone MGC:28252 IMAGE:3995040), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Positive regulatory subunit of the cyclin-dependent kinase CDK14/PFTK1. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Positive regulatory subunit of the cyclin-dependent kinase CDK16.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 39.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ccny cyclin Y [ Mus musculus (house mouse) ]
• Official Symbol: Ccny
• Synonyms: Ccny; cyclin Y; 1700025H17Rik; 3110050L10Rik; 4631402G10Rik; 5730405I09Rik; cyclin-Y; cyclin fold protein 1
• Gene ID: 67974
• mRNA Refseq: NM_026484
• Protein Refseq: NP_080760
• UniProt ID: Q8BGU5