Recombinant Mouse Casp2 Protein, His-tagged

• Cat.No.: Casp2-297M
• Product Overview: Recombinant Mouse Casp2(Gly170~Asp333) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes the evolutionarily ancient and most conserved member of the cysteine proteases that plays important role in stress-induced apoptosis, DNA repair and tumor suppression. Mice lacking the encoded protein develop normally but display cell type-specific apoptotic defects. Germ cells and oocytes from such mice were found to be resistant to cell death after treatment with chemotherapeutic drugs.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 19.9kDa
• Identity: Reconstitute in PBS or others
• Protein length: Gly170~Asp333
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: Casp2 caspase 2 [ Mus musculus ]
• Official Symbol: Casp2
• Synonyms: CASP2; caspase 2; caspase-2; CASP-2; NEDD-2; protease ICH-1; neural precursor cell expressed developmentally down-regulated protein 2; ICH-1; Nedd2; Caspase-2
• Gene ID: 12366
• mRNA Refseq: NM_007610
• Protein Refseq: NP_031636
• UniProt ID: P55159