Recombinant Mouse Calnexin Protein, His-tagged

• Cat.No.: Canx-305M
• Product Overview: Recombinant Mouse Canx (NP_031623.1) (Met1-Pro482) was expressed with a polyhistidine tag at the C-terminus.

Specification

• Species: Mouse
• Source: HEK293
• Tag: His
• Protein Length: Met1-Pro482
• Description: Calnexin is a calcium-binding protein that belongs to the calreticulin family. It interacts with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Ass centigradeiated with partial T-cell antigen receptor complexes that escape the ER of immature thym centigradeytes, it may function as a signaling complex regulating thym centigradeyte maturation. Additionally it may play a role in receptor-mediated end centigradeytosis at the synapse.
• Predicted N Terminal: His 21
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant mouse Canx consists of 473 amino acids and predicts a molecular mass of 53.9 kDa.
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 90 % as determined by SDS-PAGE.
• Storage: Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: Canx calnexin [ Mus musculus ]
• Official Symbol: Canx
• Synonyms: CANX; calnexin; Cnx; AI988026; D11Ertd153e; 1110069N15Rik
• Gene ID: 12330
• mRNA Refseq: NM_001110499
• Protein Refseq: NP_001103969