Recombinant Mouse Bmp7 protein, His-tagged

• Cat.No.: Bmp7-568M
• Product Overview: Recombinant Mouse Bmp7 (P23359) aa. (Ser292~His430) fused with His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Mutation of this gene results in skeletal, kidney, and other developmental defects.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 16.9kDa; Accurate Molecular Mass: 16kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Ser292~His430
• Purity: >98%
• Characteristic: Isoelectric point is 8.5.
• Applications: Cell culture; Activity Assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: 20mM Tris, 150mM NaCl,pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Information

• Gene Name: Bmp7 bone morphogenetic protein 7 [ Mus musculus (house mouse) ]
• Official Symbol: Bmp7
• Synonyms: Bmp7; bone morphogenetic protein 7; OP1; bone morphogenetic protein 7; osteogenic protein 1
• Gene ID: 12162
• mRNA Refseq: NM_007557.3
• Protein Refseq: NP_031583.2
• UniProt ID: P23359