Recombinant Mouse Bhlha15 Protein, Myc/DDK-tagged

• Cat.No.: Bhlha15-1862M
• Product Overview: Purified recombinant protein of mouse full-length basic helix-loop-helix family, member a15 (Bhlha15), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays a role in controlling the transcriptional activity of MyoD, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
• Molecular Mass: 22.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Bhlha15 basic helix-loop-helix family, member a15 [ Mus musculus (house mouse) ]
• Official Symbol: Bhlha15
• Synonyms: BHLHA15; basic helix-loop-helix family, member a15; class A basic helix-loop-helix protein 15; MIST-1; class B basic helix-loop-helix protein 8; muscle, intestine and stomach expression 1; basic helix-loop-helix domain containing, class B, 8; Mist1; Bhlhb8; 1810009C13Rik
• Gene ID: 17341
• mRNA Refseq: NM_010800
• Protein Refseq: NP_034930
• UniProt ID: Q9QYC3