Recombinant Mouse Bend3 Protein, Myc/DDK-tagged

• Cat.No.: Bend3-1857M
• Product Overview: Purified recombinant protein of mouse full-length BEN domain containing 3 (Bend3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination. Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites. Stimulates the ERCC6L translocase and ATPase activities.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 94.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Bend3 BEN domain containing 3 [ Mus musculus (house mouse) ]
• Official Symbol: Bend3
• Synonyms: Bend3; BEN domain containing 3; mKIAA1553; BEN domain-containing protein 3
• Gene ID: 331623
• mRNA Refseq: NM_199028
• Protein Refseq: NP_950193
• UniProt ID: Q6PAL0