Recombinant Mouse Bace2 protein, His & GST-tagged

• Cat.No.: Bace2-1832M
• Product Overview: Recombinant Mouse Bace2 aa. (Glu156~Val407 (Accession # Q9JL18)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Mouse
• Source: E.coli
• Tag: GST&His
• Protein Length: Glu156~Val407
• Description: This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein undergoes proteolytic processing to generate an active endopeptidase enzyme. This transmembrane protease catalyzes the proteolysis of amyloid precursor protein to produce amyloid beta peptide. Mice lacking the encoded product exhibit increased pancreatic beta cell mass and improved glucose tolerance due to increased insulin secretion.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 59.7kDa.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.5.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Bace2 beta-site APP-cleaving enzyme 2 [ Mus musculus (house mouse) ]
• Official Symbol: Bace2
• Synonyms: C1qa; complement component 1, q subcomponent, alpha polypeptide; C1q; AI255395; complement C1q subcomponent subunit A
• Gene ID: 56175
• mRNA Refseq: NM_019517.5
• Protein Refseq: NP_062390.3
• UniProt ID: Q9JL18