Recombinant Mouse Atrn Protein, MYC/DDK-tagged

• Cat.No.: Atrn-825M
• Product Overview: Purified recombinant protein of full-length mouse attractin (Atrn), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a widely expressed transmembrane glycoprotein that plays important roles in diverse physiological processes such as regulation of hair pigmentation, monocyte-T cell interaction and control of energy homeostasis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the mahogany mouse phenotype of dark brown or black coat on a normally agouti background. Mice with loss-of-function mutations in this gene exhibit black coat color, tremor, adiposity, higher basal metabolic rate, juvenile-onset hypomyelination and age-dependent spongiform neurodegeneration of the central nervous system.
• Molecular Mass: 158.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Atrn attractin [ Mus musculus (house mouse) ]
• Official Symbol: Atrn
• Synonyms: Atrn; attractin; mg; Mgca; AW558010; attractin; protein mahogany
• Gene ID: 11990
• mRNA Refseq: NM_009730
• Protein Refseq: NP_033860
• UniProt ID: Q9WU60