Recombinant Mouse Arrb1 protein, His-tagged

• Cat.No.: ARRB1-1857M
• Product Overview: Recombinant Arrb1 protein (Pro182-Glu359), fused to His-tag at N-terminus,, was expressed in E.coli.

Specification

• Description: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
• Source: E.coli
• Species: Mouse
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Protein length: 178
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.

Gene Information

• Gene Name: Arrb1
• Official Symbol: Arrb1
• Synonyms: ARB1; ARR1; ARR-B1; Arrestin 2
• Gene ID: 109689
• mRNA Refseq: NM_177231.2
• Protein Refseq: NP_796205.1
• UniProt ID: Q8BWG8