Recombinant Mouse Arap3 Protein, MYC/DDK-tagged

• Cat.No.: Arap3-317M
• Product Overview: Purified recombinant protein of full-length mouse ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 (Arap3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 170.2 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [ Mus musculus (house mouse) ]
• Official Symbol: Arap3
• Synonyms: Arap3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3; Drag1; Centd3; cnt-d3; E030006K04Rik; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; ARF-GAP, RHO-GAP, ankyrin repeat and pleckstrin homology domains-containing protein 3; centaurin, delta 3; dual-specificity Rho- and Arf-GTPase activating protein 1
• Gene ID: 106952
• mRNA Refseq: NM_139206
• Protein Refseq: NP_631945
• UniProt ID: Q8R5G7