Recombinant Mouse Apoo Protein, Myc/DDK-tagged

• Cat.No.: Apoo-1665M
• Product Overview: Purified recombinant protein of mouse full-length apolipoprotein O (Apoo), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function. Can induce cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts. Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 22.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Apoo apolipoprotein O [ Mus musculus (house mouse) ]
• Official Symbol: Apoo
• Synonyms: APOO; apolipoprotein O; 0610008C08Rik; 1110019O03Rik; RP23-272D10.2; MGC130105; MGC130106
• Gene ID: 68316
• mRNA Refseq: NM_026673
• Protein Refseq: NP_080949
• UniProt ID: Q9DCZ4