Recombinant Mouse Aplp1 Protein, His-tagged

• Cat.No.: Aplp1-295M
• Product Overview: Recombinant Mouse Aplp1 (NP_031493.2) (Met1-Glu584) was expressed with a polyhistidine tag at the C-terminus.

Specification

• Species: Mouse
• Source: HEK293
• Tag: His
• Protein Length: Met1-Glu584
• Description: APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-ass centigradeiated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.
• Predicted N Terminal: Asn 39
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant mouse Aplp1 consists of 557 amino acids and predicts a molecular mass of 62.4 kDa.
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 95 % as determined by SDS-PAGE.
• Storage: Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: Aplp1 amyloid beta (A4) precursor-like protein 1 [ Mus musculus ]
• Official Symbol: Aplp1
• Synonyms: APLP1; amyloid beta (A4) precursor-like protein 1; amyloid-like protein 1; APLP; APLP-1
• Gene ID: 11803
• mRNA Refseq: NM_007467
• Protein Refseq: NP_031493