Recombinant Mouse Antxr2 Protein, His-tagged

• Cat.No.: Antxr2-45M
• Product Overview: Recombinant mouse ANTXR2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Mouse
• Source: Insect Cells
• Tag: His
• Description: ANTXR2, also known as anthrax toxin receptor 2, is a widely expressed anthrax toxin receptor family protein. The main functional domain of this protein is an extracellular integrinlike von Willebrand factor type A (VWA) domain with a metal ion dependent adhesion site, through which it adheres selectively to collagen type IV and laminin. This protein and the related protein ATR/TEM8 serve as receptors for the protective antigen of Bacillus anthracis.
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 31.9kDa (295aa)28-40KDa (SDS–PAGE under reducing conditions.)
• AA Sequence: QAQEQPSCKK AFDLYFVLDK SGSVANNWIE IYNFVHQLTE RFVSPEMRLS FIVFSSQATI ILPLTGDRYK IGKGLEDLKA VKPVGETYIH EGLKLANEQI QNAGGLKASS IIIALTDGKL DGLVPSYAEN EAKKSRSLGA SVYCVGVLDF EQAQLERIAD SKDQVFPVKG GFQALKGIIN SILAQSCTEI LELSPSSVCV GEKFQVVLTG RAVTSISHDG SVLCTFTANS TYTKSEKPVS IQPSSILCPA PVLNKDGETL EVSISYNDGK SAVSRSLTIT ATECTNGLEH HHHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Antxr2 anthrax toxin receptor 2 [ Mus musculus ]
• Official Symbol: Antxr2
• Synonyms: ANTXR2; anthrax toxin receptor 2; CMG2; CMG-2; cI-35; AW561899; 2310046B19Rik
• Gene ID: 71914
• mRNA Refseq: NM_133738
• Protein Refseq: NP_598499
• Function: metal ion binding; receptor activity