Recombinant Mouse Aak1 Protein, His&GST-tagged

• Cat.No.: Aak1-06M
• Product Overview: Recombinant Mouse Aak1 Protein (Met1-Leu289) with N-His&GST tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: GST&His
• Protein Length: Met1-Leu289
• Description: Predicted to enable AP-2 adaptor complex binding activity; Notch binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including positive regulation of Notch signaling pathway; protein stabilization; and regulation of clathrin-dependent endocytosis. Predicted to act upstream of or within endocytosis and phosphorylation. Predicted to be located in cell leading edge and terminal bouton. Predicted to be part of clathrin complex. Predicted to be active in cytoplasm. Is expressed in cranial ganglion; dorsal root ganglion; retina nuclear layer; and telencephalon. Orthologous to human AAK1 (AP2 associated kinase 1).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 62 kDa
  Accurate Molecular Mass: 62 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Aak1 AP2 associated kinase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Aak1
• Synonyms: AAK1; AP2 associated kinase 1; adaptor-associated kinase 1; C79663; R75501; AU067724; AU067726; BC028270; mKIAA1048; 9630042K20; D6Ertd245e; 5530400K14Rik; MGC40785
• Gene ID: 269774
• mRNA Refseq: NM_001040106
• Protein Refseq: NP_001035195
• UniProt ID: Q3UHJ0