Recombinant Influenza [A/Thailand/1(KAN-1)/2004(H5N1)] Neuraminidase (NA) protein, His-tagged

• Cat.No.: NA-346I
• Product Overview: Recombinant Influenza [A/Thailand/1(KAN-1)/2004(H5N1)] Neuraminidase (NA) protein (His36-Lys449), fused to His tag at N-terminus, was expressed in human 293 cells (HEK293).

Specification

• Species: Influenza [A/Thailand/1(KAN-1)/2004(H5N1)]
• Source: HEK293
• Tag: His
• Protein Length: 414
• Description: Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
• Form: Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 46.1 kDa. The protein migrates as 48 kDa under reducing (R) condition (SDS-PAGE).
• Endotoxin: Less than 1.0 EU per ug by the LAL method.
• Purity: >92% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 centigrade to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Official Symbol: NA
• UniProt ID: H8PF47