Recombinant Human ZWINT Protein, His-tagged

Cat.No. : ZWINT-458H
Product Overview : Recombinant Human ZWINT(Met1-Pro277), transcript variant 3, fused with His tag at C-terminal was expressed in E. coli.
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Description : THis gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for tHis gene.
Source : E. coli
Tag : His
Form : Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Molecular Mass : 33.4 kDa
Endotoxin : < 0.1 EU per µg protein as determined by LAL test
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : Resuspend the protein to the desired concentration in proper buffer.
Protein length : 1-277 a.a.
Gene Name ZWINT ZW10 interactor [ Homo sapiens ]
Official Symbol ZWINT
Synonyms ZWINT; ZW10 interactor; KNTC2AP; zwint-1; ZW10-interacting protein 1; human ZW10 interacting protein-1; ZWINT1; HZwint-1; MGC117174;
Gene ID 11130
mRNA Refseq NM_001005413
Protein Refseq NP_001005413
MIM 609177
UniProt ID O95229

Not For Human Consumption!

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