Recombinant Human ZNHIT1, His-tagged

• Cat.No.: ZNHIT1-134H
• Product Overview: ZNHIT1, 1-154aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-154aa
• Description: ZNHIT1 belongs to the ZNHIT1 family and contains 1 HIT-type zinc finger. The protein is induced by DNA damage and seems to play role in p53-mediated apoptosis induction. ZNHIT1 interacts with MAPK11 and MAPK14 and is component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1. Recombinant human ZNHIT1 protein, fused to His-tag at N-terminus, was expressed in E.coli .
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
• Molecular Mass: 19.9 kDa (177aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMVEKKTS VRSQDPGQRR VLDRAARQRR INRQLEALEN DNFQDDPHAG LPQLGKRLPQ FDDDADTGKK KKKTRGDHFK LRFRKNFQAL LEEQNLSVAE GPNYLTACAG PPSRPQRPFC AVCGFPSPYT CVSCGARYCT VRCLGTHQET RCLKWTV
• Purity: >95 % by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ZNHIT1 zinc finger, HIT-type containing 1 [ Homo sapiens ]
• Official Symbol: ZNHIT1
• Synonyms: ZNHIT1; zinc finger, HIT-type containing 1; zinc finger protein, subfamily 4A (HIT domain containing), member 1 , zinc finger, HIT domain containing 1 , ZNFN4A1; zinc finger HIT domain-containing protein 1; CG1I; H_DJ0747G18.14; putative cyclin G1 interacting protein; p18Hamlet; p18 Hamlet; zinc finger, HIT type 1; cyclin-G1-binding protein 1; zinc finger, HIT domain containing 1; zinc finger protein subfamily 4A member 1; zinc finger protein, subfamily 4A (HIT domain containing), member 1; ZNFN4A1
• Gene ID: 10467
• mRNA Refseq: NM_006349
• Protein Refseq: NP_006340
• UniProt ID: O43257
• Chromosome Location: 7q22.1
• Function: metal ion binding; protein binding