Recombinant Human ZMAT3, His-tagged

• Cat.No.: ZMAT3-15896H
• Product Overview: Recombinant human ZMAT3 protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-289aa
• Description: ZMAT3 is a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
• Molecular Mass: 34.4 kDa (312aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMILLQHA VLPPPKQPSP SPPMSVATRS TGTLQLPPQK PFGQEASLPL AGEEELSKGG EQDCALEELC KPLYCKLCNV TLNSAQQAQA HYQGKNHGKK LRNYYAANSC PPPARMSNVV EPAATPVVPV PPQMGSFKPG GRVILATEND YCKLCDASFS SPAVAQAHYQ GKNHAKRLRL AEAQSNSFSE SSELGQRRAR KEGNEFKMMP NRRNMYTVQN NSAGPYFNPR SRQRIPRDLA MCVTPSGQFY CSMCNVGAGE EMEFRQHLES KQHKSKVSEQ RYRNEMENLG YV
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ZMAT3 zinc finger, matrin-type 3 [ Homo sapiens ]
• Official Symbol: ZMAT3
• Synonyms: ZMAT3; zinc finger, matrin-type 3; zinc finger matrin-type protein 3; FLJ12296; MGC10613; PAG608; WIG 1; WIG1; WIG-1/PAG608 protein; zinc finger protein WIG1; zinc finger protein WIG-1; zinc finger, matrin type 3; p53 target zinc finger protein; p53-activated gene 608 protein; WIG-1; FLJ31683
• Gene ID: 64393
• mRNA Refseq: NM_022470
• Protein Refseq: NP_071915
• MIM: 606452
• UniProt ID: Q9HA38
• Chromosome Location: 3q26.32
• Pathway: p53 signaling pathway, organism-specific biosystem; p53 signaling pathway, conserved biosystem
• Function: RNA binding; metal ion binding; zinc ion binding