Recombinant Human zinc ribbon domain containing 1, His-tagged

• Cat.No.: ZNRD1-318H
• Product Overview: ZNRD1, 1-126aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-126 a.a.
• Description: ZNRD1 is a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I. Alternate splicing of this gene results in two transcript variants encoding the same protein. Additional splice variants have been described, but their full-length sequences have not been determined. Recombinant human ZNRD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 16.3 kDa (149aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSVMDLA NTCSSFQSDL DFCSDCGSVL PLPGAQDTVT CIRCGFNINV RDFEGKVVKT SVVFHQLGTA MPMSVEEGPE CQGPVVDRRC PRCGHEGMAY HTRQMRSADE GQTVFYTCTN CKFQEKEDS
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ZNRD1 zinc ribbon domain containing 1 [ Homo sapiens ]
• Official Symbol: ZNRD1
• Synonyms: ZNRD1; zinc ribbon domain containing 1; zinc ribbon domain containing, 1; DNA-directed RNA polymerase I subunit RPA12; HTEX 6; hZR14; RPA12; tctex 6; zinc ribbon domain-containing protein 1; transcription-associated zinc ribbon protein; RNA polymerase I small specific subunit Rpa12; TEX6; Rpa12; HTEX-6; tctex-6; MGC13376
• Gene ID: 30834
• mRNA Refseq: NM_014596
• Protein Refseq: NP_055411
• MIM: 607525
• UniProt ID: Q9P1U0
• Chromosome Location: 6p21
• Pathway: Metabolic pathways, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem; RNA polymerase, organism-specific biosystem; RNA polymerase, conserved biosystem
• Function: DNA-directed RNA polymerase activity; metal ion binding; nucleic acid binding; zinc ion binding