Recombinant Human ZFYVE27 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ZFYVE27-2561H
• Product Overview: ZFYVE27 MS Standard C13 and N15-labeled recombinant protein (NP_001002261) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 46.2 kDa
• AA Sequence: MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDGVRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDSELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPVVSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEEHAFESPPPPDVGGKDGLMDSTPALTPTESLSSQDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSKTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ZFYVE27 zinc finger FYVE-type containing 27 [ Homo sapiens (human) ]
• Official Symbol: ZFYVE27
• Synonyms: ZFYVE27; zinc finger FYVE-type containing 27; SPG33; PROTRUDIN; protrudin; spastic paraplegia 33 protein; zinc finger FYVE domain containing 27
• Gene ID: 118813
• mRNA Refseq: NM_001002261
• Protein Refseq: NP_001002261
• MIM: 610243
• UniProt ID: Q5T4F4