Recombinant Human YJU2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: YJU2-2654H
• Product Overview: CCDC94 MS Standard C13 and N15-labeled recombinant protein (NP_060544) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 37.1 kDa
• AA Sequence: MSERKVLNKYYPPDFDPSKIPKLKL PKDRQYVVRLMAPFNMRCKTCGEYI YKGKKFNARKETVQNEVYLGLPIFR FYIKCTRCLAEITFKTDPENTDYTM EHGATRNFQAEKLLEEEEKRVQKER EDEELNNPMKVLENRTKDSKLEMEV LENLQELKDLNQRQAHVDFEAMLRQ HRLSEEERRRQQQEEDEQETAALLE EARKRRLLEDSDSEDEAAPSPLQPA LRPNPTAILDEAPKPKRKVEVWEQS VGSLGSRPPLSRLVVVKKAKADPDC SNGQPQAAPTPGAPQNRKEANPTPL TPGASSLSQLGAYLDSDDSNGSNTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: YJU2 YJU2 splicing factor homolog [ Homo sapiens (human) ]
• Official Symbol: YJU2
• Synonyms: YJU2; YJU2 splicing factor homolog; CCDC94; splicing factor YJU2; coiled-coil domain containing 94; coiled-coil domain-containing protein 94
• Gene ID: 55702
• mRNA Refseq: NM_018074
• Protein Refseq: NP_060544
• UniProt ID: Q9BW85