Recombinant Human YARS2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: YARS2-4094H
• Product Overview: YARS2 MS Standard C13 and N15-labeled recombinant protein (NP_001035526) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2).
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 53.2 kDa
• AA Sequence: MAAPILRSFSWGRWSGTLNLSVLLP LGLRKAHSGAQGLLAAQKARGLFKD FFPETGTKIELPELFDRGTASFPQT IYCGFDPTADSLHVGHLLALLGLFH LQRAGHNVIALVGGATARLGDPSGR TKEREALETERVRANARALRLGLEA LAANHQQLFTDGRSWGSFTVLDNSA WYQKQHLVDFLAAVGGHFRMGTLLS RQSVQLRLKSPEGMSLAEFFYQVLQ AYDFYYLFQRYGCRVQLGGSDQLGN IMSGYEFINKLTGEDVFGITVPLIT STTGAKLGKSAGNAVWLNRDKTSPF ELYQFFVRQPDDSVERYLKLFTFLP LPEIDHIMQLHVKEPERRGPQKRLA AEVTKLVHGREGLDSAKRCTQALYH SSIDALEVMSDQELKELFKEAPFSE FFLDPGTSVLDTCRKANAIPDGPRG YRMITEGGVSINHQQVTNPESVLIV GQHILKNGLSLLKIGKRNFYIIKWL QLTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: YARS2 tyrosyl-tRNA synthetase 2 [ Homo sapiens (human) ]
• Official Symbol: YARS2
• Synonyms: YARS2; tyrosyl-tRNA synthetase 2, mitochondrial; tyrosine--tRNA ligase, mitochondrial; CGI 04; FLJ13995; mt TyrRS; tyrosine tRNA ligase 2; mitochondrial; tyrosine tRNA ligase 2, mitochondrial; TYRRS; CGI-04; MLASA2; MT-TYRRS
• Gene ID: 51067
• mRNA Refseq: NM_001040436
• Protein Refseq: NP_001035526
• MIM: 610957
• UniProt ID: Q9Y2Z4