Recombinant Human XRCC1 Protein, MYC/DDK-tagged

• Cat.No.: XRCC1-1500H
• Product Overview: Recombinant Human XRCC1 Protein was expressed in human HEK293 cells with C-terminal MYC/DDK-tag.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
• Form: Liquid
• Molecular Mass: 69.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 [ Homo sapiens ]
• Official Symbol: XRCC1
• Synonyms: XRCC1; X-ray repair complementing defective repair in Chinese hamster cells 1; RCC; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1; X-ray-repair, complementing defective, repair in Chinese hamster
• Gene ID: 7515
• mRNA Refseq: NM_006297
• Protein Refseq: NP_006288
• MIM: 194360
• UniProt ID: P18887