Recombinant Human XPNPEP1, His-tagged

• Cat.No.: XPNPEP1-87H
• Product Overview: Recombinant human XPNPEP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: XPNPEP1 also known as Xaa-Pro aminopeptidase 1 isoform 1, is encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. This product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones.
• Form: Liquid, In Phosphate buffered saline (pH7.4) containing 20% glycerol
• Molecular Mass: 73.4kDa (655aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSEFELRRQ ASMPPKVTSE LLRQLRQAMR NSEYVTEPIQ AYIIPSGDAH QSEYIAPCDC RRAFVSGFDG SAGTAIITEE HAAMWTDGRY FLQAAKQMDS NWTLMKMGLK DTPTQEDWLV SVLPEGSRVG VDPLIIPTDY WKKMAKVLRS AGHHLIPVKE NLVDKIWTDR PERPCKPLLT LGLDYTGISW KDKVADLRLK MAERNVMWFV VTALDEIAWL FNLRGSDVEH NPVFFSYAII GLETIMLFID GDRIDAPSVK EHLLLDLGLE AEYRIQVHPY KSILSELKAL CADLSPREKV WVSDKASYAV SETIPKDHRC CMPYTPICIA KAVKNSAESE GMRRAHIKDA VALCELFNWL EKEVPKGGVT EISAADKAEE FRRQQADFVD LSFPTISSTG PNGAIIHYAP VPETNRTLSL DEVYLIDSGA QYKDGTTDVT RTMHFGTPTA YEKECFTYVL KGHIAVSAAV FPTGTKGHLL DSFARSALWD SGLDYLHGTG HGVGSFLNVH EGPCGISYKT FSDEPLEAGM IVTDEPGYYE DGAFGIRIEN VVLVVPVKTK YNFNNRGSLT FEPLTLVPIQ TKMIDVDSLT DKECDWLNNY HLTCRDVIGK ELQKQGRQEA LEWLIRETQP ISKQH
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble [ Homo sapiens ]
• Official Symbol: XPNPEP1
• Synonyms: XPNPEP1; X-prolyl aminopeptidase (aminopeptidase P) 1, soluble; X prolyl aminopeptidase (aminopeptidase P) like , XPNPEP, XPNPEPL, XPNPEPL1; xaa-Pro aminopeptidase 1; X-Pro aminopeptidase 1; soluble aminopeptidase P; cytosolic aminopeptidase P; aminopeptidase P, cytosolic; aminoacylproline aminopeptidase; X-prolyl aminopeptidase 1, soluble; APP1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1
• Gene ID: 7511
• mRNA Refseq: NM_001167604
• Protein Refseq: NP_001161076
• MIM: 602443
• UniProt ID: Q9NQW7
• Chromosome Location: 10q25.3
• Function: aminopeptidase activity; aminopeptidase activity; hydrolase activity; manganese ion binding; metal ion binding; metalloaminopeptidase activity; metallopeptidase activity; peptidase activity; protein homodimerization activity