Recombinant Human WWC1, His-tagged

• Cat.No.: WWC1-5053H
• Product Overview: Recombinant human WWC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: WWC1 is a cytoplasmic phosphoprotein that interacts with PRKC-zeta and dynein light chain-1. Alleles of WWC1 have been found that enhance memory in some individuals. Three transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 17.0 kDa (152aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSEAVGATR IQIALKYDEK NKQFAILIIQ LSNLSALLQQ QDQKVNIRVA VLPCSESTTC LFRTRPLDAS DTLVFNEVFW VSMSYPALHQ KTLRVDVCTT DRSHLEECLG GAQISLAEVC RSGERSTRWY NL
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: WWC1 WW and C2 domain containing 1 [ Homo sapiens ]
• Official Symbol: WWC1
• Synonyms: WWC1; WW and C2 domain containing 1; WW, C2 and coiled coil domain containing 1; protein KIBRA; KIAA0869; KIBRA; protein WWC1; HBeAg-binding protein 3; kidney and brain protein; WW, C2 and coiled-coil domain containing 1; HBEBP3; HBEBP36; FLJ10865; FLJ23369
• Gene ID: 23286
• mRNA Refseq: NM_001161661
• Protein Refseq: NP_001155133
• UniProt ID: Q8IX03
• Chromosome Location: 5q34
• Pathway: Signal Transduction, organism-specific biosystem; Signaling by Hippo, organism-specific biosystem
• Function: protein binding; transcription coactivator activity