Recombinant Human WNT8A protein, MYC/DDK-tagged

• Cat.No.: WNT8A-254H
• Product Overview: Recombinant Human WNT8A fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. Multiple alternatively spliced transcript variants have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 38.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: WNT8A wingless-type MMTV integration site family, member 8A [ Homo sapiens ]
• Official Symbol: WNT8A
• Synonyms: WNT8A; wingless-type MMTV integration site family, member 8A; protein Wnt-8a; WNT8D; WNT8d; protein Wnt-8d
• Gene ID: 7478
• mRNA Refseq: NM_058244
• Protein Refseq: NP_490645
• MIM: 606360
• UniProt ID: Q9H1J5
• Chromosome Location: 5q31
• Pathway: Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Hedgehog signaling pathway, organism-specific biosystem
• Function: G-protein coupled receptor binding; frizzled binding; receptor agonist activity