Recombinant Human WNT10A Protein

• Cat.No.: WNT10A-111H
• Product Overview: The mature recombinant human Wnt-10a protein containing 382aa (Q36-K417) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.
• Molecular Mass: 44 kDa
• Product-Related Proteins: 36-417
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: WNT10A Wnt family member 10A [ Homo sapiens (human) ]
• Official Symbol: WNT10A
• Synonyms: WNT10A; Wnt family member 10A; OODD; SSPS; STHAG4; protein Wnt-10a; Names; wingless-type MMTV integration site family, member 10A
• Gene ID: 80326
• mRNA Refseq: NM_025216
• Protein Refseq: NP_079492
• MIM: 606268
• UniProt ID: Q9GZT5