Recombinant Human WDR45L, His-tagged

• Cat.No.: WDR45L-31542TH
• Product Overview: Recombinant fragment, corresponding to amino acids 139-344 of Human WDR45L with N terminal His tag; 206 amino acids, 25kDa.

Specification

• Description: This gene encodes a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein-protein interactions, and a conserved motif for interaction with phospholipids. The human genome contains several pseudogenes of this gene.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Ubiquitously expressed. Highly expressed in heart, skeletal muscle and pancreas. Up-regulated in a variety of tumor tissues including ovarian and uterine cancers.
• Form: Lyophilised:Reconstitute with 104 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: YNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPP VDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTS SGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHI FAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSG SPCICAFGTEPNAVIAICADGSYYKFLFNPKGECIRDV YAQFLEMTDDKL
• Sequence Similarities: Belongs to the WD repeat SVP1 family.Contains 2 WD repeats.
• Protein length: 139-344 a.a.

Gene Information

• Gene Name: WDR45L WDR45-like [ Homo sapiens ]
• Official Symbol: WDR45L
• Synonyms: WDR45L; WDR45-like; WD repeat domain phosphoinositide-interacting protein 3; WIPI3
• Gene ID: 56270
• mRNA Refseq: NM_019613
• Protein Refseq: NP_062559
• MIM: 609226
• Uniprot ID: Q5MNZ6
• Chromosome Location: 17q25.3
• Function: phosphatidylinositol-3,5-bisphosphate binding