Recombinant Human VWF, DDK-tagged

• Cat.No.: VWF-2713H
• Product Overview: Recombinant human VWF, was expressed in sf9 cells, Met-Ala2200-Lys2813, with C-terminal DDK tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: Flag
• Protein Length: Met-Ala2200-Lys2813
• Description: The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22.
• Form: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
• Molecular Mass: 67 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: VWF von Willebrand factor [ Homo sapiens ]
• Official Symbol: VWF
• Synonyms: VWD; F8VWF; von Willebrand factor; coagulation factor VIII VWF
• Gene ID: 7450
• mRNA Refseq: NM_000552
• Protein Refseq: NP_000543
• MIM: 613160
• UniProt ID: P04275
• Chromosome Location: 12p13.3
• Pathway: Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem
• Function: chaperone binding; collagen binding; glycoprotein binding