Recombinant Human VRK2 Protein, His&GST-tagged

• Cat.No.: VRK2-574H
• Product Overview: Recombinant Human VRK2 Protein (Met1-Gln290) with N-His&GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 63.2 kDa
  Accurate Molecular Mass: 63 kDa
• Protein length: Met1-Gln290
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: VRK2 vaccinia related kinase 2 [ Homo sapiens (human) ]
• Official Symbol: VRK2
• Synonyms: VRK2; vaccinia related kinase 2; serine/threonine-protein kinase VRK2; vaccinia virus B1R-related kinase 2
• Gene ID: 7444
• mRNA Refseq: NM_001130480
• Protein Refseq: NP_001123952
• MIM: 602169
• UniProt ID: Q86Y07