Recombinant Human VOPP1, His-tagged

• Cat.No.: VOPP1-3540H
• Product Overview: Recombinant humanVOPP1 protein, fused to His-tag at N-terminus, was expressed in E. coliand purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: VOPP1 has beenpreviously shown to be over-expressed in human glioblastoma multiforme andsquamous cell carcinoma. VOPP1 is a key regulator of NF-kappa-B signaling,and that high-level, amplification-mediated VOPP1 expression, such as thatoccurring in tumors with amplified EGFR, could contribute to resistance toapoptosis.
• Application: SDS-PAGE
• Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.2M NaCl.
• Molecular Weight: 12 kDa (112aa),confirmed by MALDI-TOF
• Purity: > 90% by SDS-PAGE
• Concentration: 0.5 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MCPPPPAYCNT PPPPYEQVVK AK RRRMYPPPL IEEPAFNVSYTRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQV PPNSPQGSVA
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: VOPP1

Gene Information

• Gene Name: VOPP1 vesicular, overexpressedin cancer, prosurvival protein 1 [ Homo sapiens ]
• Synonyms: VOPP1; vesicular,overexpressed in cancer, prosurvival protein 1; ECOP;GASP; FLJ20532; DKFZp564K0822; OTTHUMP00000209214; OTTHUMP00000209215; OTTHUMP00000209216;OTTHUMP00000209217; OTTHUMP00000209218; OTTHUMP00000209219; OTTHUMP00000209220;OTTHUMP00000209221; OTTHUMP00000209222; OTTHUMP00000209223; OTTHUMP00000209224;OTTHUMP00000209225; OTTHUMP00000209226; Glioblastoma-amplified secreted protein;EGFR-coamplified and overexpressed protein; putative NF-kappa-B-activatingprotein 055N; ECop
• Gene ID: 81552
• mRNA Refseq: NM_030796
• Protein Refseq: NP_110423
• MIM: 611915
• UniProt ID: Q96AW1
• Chromosome Location: 7p11.2
• Function: Signal transducer activity