Recombinant Human Vesicular, Overexpressed In Cancer, Prosurvival Protein 1, His-tagged

• Cat.No.: VOPP1-5155H
• Product Overview: Recombinant human VOPP1 protein,fused to His-tag at N-terminus, was expressed in E. coli and purified byusing conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: Vesicular, overexpressed in cancer,prosurvival protein 1(VOPP1), also known as Glioblastoma-amplified secretedprotein (GASP), has been previously shown to be over-expressed in humanglioblastoma multiforme and squamous cell carcinoma. VOPP1 is a key regulatorof NF-kappaB signaling, and that high-level, amplification-mediated VOPP1expression, such as that occurring in tumors with amplified EGFR, couldcontribute to resistance to apoptosis.
• Concentration: 0.5 mg/ml
• Form: Supplied as aliquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 30% glycerol and0.2M NaCl.
• Purity: > 90% by SDS - PAGE
• Sequence: 82-172 amino acids: MGSSHHHHHHSSGLVPRGSH MRRRMYPPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQVPPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK
• Molecular Mass: 12 kDa (112aa), confirmed by MALDI-TOF
• Applications: SDS-PAGE
• Storage: Store at 4 deg Cfor short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: VOPP1

Gene Information

• Gene Name: VOPP1 vesicular, overexpressed in cancer, prosurvivalprotein 1 [ Homo sapiens ]
• Synonyms: VOPP1; vesicular,overexpressed in cancer, prosurvival protein 1; ECOP; GASP; FLJ20532;DKFZp564K0822; vesicular,overexpressed in cancer, prosurvival protein 1; OTTHUMP00000209214; OTTHUMP00000209217;OTTHUMP00000209218; OTTHUMP00000209221; Glioblastoma-amplified secretedprotein; EGFR-coamplified and overexpressed protein
• Gene ID: 81552
• mRNA Refseq: NM_030796
• Protein Refseq: NP_110423
• MIM: 611915
• UniProt ID: Q96AW1
• Chromosome Location: 7p11.2
• Function: signaltransducer activity