Recombinant Human VDR, GST-tagged

• Cat.No.: VDR-118H
• Product Overview: Recombinant Human GST-tagged Vitamin D receptor ligand-binding domain (VDR-LBD) consists of a 218 a.a. GST tag, a 13 a.a. flexible linker and a 322 a.a. VDR-LBD, Acc# NP_000367.1, amino acids 105-427, was produced in insect cells infected with a recombinant baculovirus.

Specification

• Source: Sf9 insect cells
• Species: Human
• Tag: GST
• Form: 20 mM Na-P pH 8.0, 40 mM KCl, 20 mM Na2MoO4, 7 mM reduced glutathione, 15% glycerol.
• Purity: >90%
• Applications: Ligand binding and coactivator peptide recruitment assays.
• Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.

Gene Information

• Gene Name: VDR vitamin D (1,25- dihydroxyvitamin D3) receptor [ Homo sapiens ]
• Official Symbol: VDR
• Synonyms: VDR; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D3 receptor; NR1I1; 1,25-dihydroxyvitamin D3 receptor; vitamin D nuclear receptor variant 1; nuclear receptor subfamily 1 group I member 1
• Gene ID: 7421
• mRNA Refseq: NM_000376
• Protein Refseq: NP_000367
• MIM: 601769
• UniProt ID: P11473
• Chromosome Location: 12q12-q14
• Pathway: Direct p53 effectors, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem
• Function: DNA binding; metal ion binding; protein binding; receptor activity; retinoid X receptor binding; sequence-specific DNA binding; contributes_to sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; contributes_to vitamin D response element binding; vitamin D3 receptor activity; zinc ion binding