Recombinant Human Vascular Endothelial Growth Factor A, His-tagged

Cat.No. : VEGFA-713H
Product Overview : Recombinant HumanVEGF with His tag is a non-glycosylated, monomeric polypeptide chaincontaining a fragment of 165 amino acids (aa 5-169) and an N-terminal Histag.
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Species : Human
Source : E.coli
Tag : His
Protein Length : 5-169 a.a.
Description : VEGFA circulatesmore freely than other VEGF forms, which bind more tightly with vascularheparin sulfates. A vascular endothelial growth factor (VEGF) mRNA speciescontaining exons 1–6 and 8 of the VEGF gene was found to be expressed as amajor VEGF mRNA form in several cell lines derived from carcinomas of thefemale reproductive system.
Form : Sterile filteredliquid in 20 mM Tris HCl, pH 8.0 + 50% glycerol + 0.05 mM DTT
Molecule weight : 23.6 kDa
Concentration : 0.053 mg/ml
Purity : > 95.0% asdetermined by RP-HPLC and SDS-PAGE analyses
Endotoxin Level : < 0.1 ng/µg ofVEGF
Storage : Stable for 4 weeksat 2-4°C. For long term storage, aliquot and store at -20°C. Avoid repeatedfreeze-thaw cycles.
OfficialSymbol : VEGFA
Gene Name VEGFA vascular endothelialgrowth factor A [ Homo sapiens ]
Synonyms VEGFA; vascularendothelial growth factor A; VPF; VEGF; MVCD1; OTTHUMP00000016487;OTTHUMP00000016488; OTTHUMP00000165985; OTTHUMP00000165986;OTTHUMP00000165987; OTTHUMP00000224107; OTTHUMP00000224108;OTTHUMP00000224109; OTTHUMP00000224153; OTTHUMP00000224154;OTTHUMP00000224423; OTTHUMP00000224424; OTTHUMP00000224425;OTTHUMP00000224426; OTTHUMP00000224427; OTTHUMP00000224428;OTTHUMP00000224429; OTTHUMP00000224430; vascular permeability factor
Gene ID 7422
mRNA Refseq NM_003376
Protein Refseq NP_003367
MIM 192240
UniProt ID P15692
Chromosome Location 6p12
Pathway Bladder cancer;Cytokine-cytokine receptor interaction; Endochondral Ossification; Focaladhesion; Glypican 1 network; HIF-1-alpha transcription factor network; IdSignaling Pathway; Neurophilin interactions with VEGF and VEGFR; Pancreaticcancer; Renal cell carcinoma; Signal Transduction; Signaling events mediatedby VEGFR1 and VEGFR2; VEGF ligand-receptor interactions; VEGFR1 specificsignals; mTOR signaling pathway
Function cell surfacebinding; chemoattractant activity; cytokine activity; extracellular matrixbinding; fibronectin binding; growth factor activity; heparin binding;platelet-derived growth factor receptor binding; protein binding; proteinheterodimerization activity; vascular endothelial growth factor receptor 1binding; vascular endothelial growth factor receptor 2 binding; vascularendothelial growth factor receptor binding

Not For Human Consumption!

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